Our Story

SpineX was created in 2019 with the commitment to deliver on the over 50 years of basic science and clinical research by Dr. V. Reggie Edgerton, distinguished professor of neurobiology at the University of California, Los Angeles. During this time, Dr. Edgerton and his colleagues have published extensively on the plasticity of the nervous system, and the concept that complex movements like stepping can be controlled by neural networks at the level of the spinal cord. Dr. Edgerton hypothesized more than 40 years ago that these spinal movement generators could perceive and respond to stimuli, and could be trained to restore lost or impaired function. By using an array of electrical stimulation patterns to activate these spinal cord networks, people who suffer functional deficits resulting from a range of pathological conditions can now improve their function and quality of life significantly. Dr. Edgerton has followed through with his commitment to develop technologies that translate his basic science discoveries to the clinic where patients can now begin to restore lost motor and physiological functions.

Dr. Edgerton, considered the “father of modern spinal neuromodulation,” continues to compile scientific evidence in humans that paralyzed patients can improve a variety of bodily functions within days of receiving neuromodulatory therapy. Dr. Edgerton and his team have demonstrated that patients continue to improve as they train. Dr. Parag Gad, a bioengineer and a long-term collaborator of Dr. Edgerton, is a cofounder of SpineX. Headquartered in Los Angeles, SpineX is currently developing non-invasive, smart medical devices for treatment of sensorimotor and autonomic dysfunctions for clinical and home use.

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